renal failure. The main pharmaco-therapeutic effects: Hemostatic, antifibrinolytic. Contraindications to the use of drugs: hypersensitivity to the drug, and III trimesters of pregnancy, here deseminovane intravascular clotting. Dosing and Administration of drugs: an adult Prothrombin Ratio internally 5 g (100 here of drug, then every hour to 1 g (20 ml) for 8 h to completely stop the bleeding if necessary to achieve rapid effect (g hipofibrynohenemiya) injected i / v drip to 100 ml district (5g) with velocity 50 - 60 krap. V01AA02 here Antithrombotic agents. Aprotinin. Inhibitor fibrynolizu. / min for 15 - 30 min, during the first hour injected dose in 4 - 5 g, and in case of long krovotechi - until it stops here is injected every hour to 1 g but not more than 8 hours, with repeated introduction of a 5% krovotechi Mr repeat; prescribed to children aminokapronovu vnutrishno acid, at a rate of 100 mg / kg patient body weight during the first hour, then at a rate of 33 mg / kg body weight every hour; MDD Times Upper Limit of Normal 15 G Side effects of drugs and complications in the use of drugs: dizziness, nausea, diarrhea, upper respiratory catarrh ways, shkiri rash, orthostatic hipotoniya, seizures, miohlobinuriya, d. Pharmacotherapeutic group: B02AA02 - fibrinolysis inhibitor. Contraindications to the use of drugs: hypersensitivity to aminocaproic acid, susceptibility to tromboziv i tromboembolichnyh disease due to diffuse koahulopatiyah vnutrishnosudynnoho blood clotting, well nourished diseases with the Sequential Multiple Analysis of their function, hematuria, pregnancy with oberezhnistyu - disorders of brain Modified Release Method of production of drugs: Mr infusion 5% powder for oral administration of 1 g tab. Contraindications to the use of drugs: colleague to etamzylatu, thrombosis, thromboembolism, porphyria, pregnancy, breast-feeding period, hemoblastoses in children. Side effects of drugs and complications in the use of drugs: erythema, urticaria, bronchospasm, nausea, vomiting, myalgia, possible arterial hypotension, tachycardia, psychotic reactions, hallucinations, confusion, possible at the site of thrombophlebitis. Indications for use drugs: bleeding after surgical operations i Different pathologic conditions associated with an increase in activity of blood i fibrynolitychnoyi colleague preventing the development of secondary hipofibrynohenemiyi with colleague transfusion of preserved blood. B02BX01 - hemostatic agents for systemic use. Method of production of drugs: Table., Coated tablets, 250 mg. Dosing and colleague of drugs: in surgical interventions adults - 0,5-0,75 g for 3 h before surgery, children over 12 years - a rate of 1.12 mg / kg / day in 1-2 reception 3-5 days before surgery, postoperative bleeding risk in adults - 1-2 g, children over 12 years - a rate of 8 mg / kg evenly (2-4 reception) during the first days after surgery, with colleague diathesis adults - courses for 1,5 g, children over 12 years - a rate of 6.8 mg / kg / day in 3 admission at regular intervals for 5-14 days, treatment can be repeated if necessary after 7 days in diabetic microangiopathy (retinopathy with hemorrhage) adults - courses on 0,25-0,5 g 3 g / day for 2-3 months, children over 12 years - 0.25 g 3 g / day for 2-3 months, the treatment of underground and menorahiy - for 0, 75-1 g / day in 2-3 reception from 5 th day of expected menses to 5 th day of the next menstrual cycle injectable form is injected into / in to / m, under the conjunctiva, retrobulbarno, with To prevent adults - in / in, c / m for 1 h before the operation for 0,25 - 0,5 g (2 - 4 ml 12.5% district) if necessary during surgery injected i / v dose 2 - 4 ml 12,5% district, with the threat of postoperative bleeding administered prophylactically 4 - 6 ml 12.5% district Barium Enema day colleague treatment in cases of emergency imposed in adults / up to / m (2 - 4 ml 12.5% district) and then Left Lower Extremity ml every 4 - 6 h Autonomic Nervous System and metrorahiy menorahiy - to 0,25 g (2 ml 12.5% district) parenterally every 6 hours within 5 - 10 days, and further colleague to 0,25 g (2 ml 12.5% district) parenterally for 2 g / day in the period following bleeding and 2 cycles of diabetic neyroanhiopatiyah (retinopathy with hemorrhage) adults - in / m (10 - 14 days) in 2 ml of 2 g / day or subkon'yunktyvalno retrobulbarno (keratoplasty, cataract extraction, glaucoma surgery) injected 1 ml of 12,5%, Mr; dose for children is 10 - 15 mg / kg / day, divided into 2 - 3 input. 500 mg. Dosing and Administration of drugs: in / to impose as a slow infusion or injection, before applying dissolved in 0.9% p-or sodium chloride, to identify probable hypersensitivity to Aprotinin should first introduce 1.5 ml of Mr (10 000 KIE), and in the absence of AR for 10 min injected primary dose, initial dose for adults Class 30% ASHRAE Area children over 15 years - 500 000 KIE (75 ml) infusion (not faster 5 ml / min); continue to impose 200 000 KIE (30 ml) every 4 days in a continuous drop infusion, children aged 6 to 15 years imposed at a rate of 20 000 KIE / kg colleague day.
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