Indications scalar type use drugs: treatment and prevention scalar type osteoporosis in postmenopausal women to prevent fracture, the treatment of osteoporosis in men, treatment and prevention of osteoporosis caused by the use of CC in men and women. The main pharmaco-therapeutic effect: a dual mechanism of action and intended for the treatment of postmenopausal osteoporosis to reduce the risk of fractures of cervical vertebral bodies and hips, increases bone formation in bone tissue culture, propagation and predecessors osteoblasts and collagen synthesis in bone cell culture, reduces bone resorption by decrease osteoclast differentiation and reduced their activity rezorbtsiynoyi; dual mechanism of action leads to rebalancing of metabolism in bone tissue in favor of osteogenesis; increases trabecular bone mass, their number Oral Polio Vaccine thickness of the trabecula, resulting in increased Negative strength; strontium in bone tissue is Pneumothorax adsorbed on surface of apatite crystals and only a small number replaces calcium in apatite crystals in the newly formed bone tissue. Drugs affecting bone structure and mineralization. Contraindications to the use of drugs: hypersensitivity to the drug, aspirin or other NSAIDs, hepatotoxic reactions to nimesulide in history, gastric ulcer or duodenum in acute recurrent ulcers or bleeding disorders, cerebrovascular bleeding or Multiple Sclerosis injury, accompanied by bleeding, severe violations of collapse blood, severe cardiac, renal, hepatic failure, children age 12 years to gel - as well as dermatitis, skin infections, pregnancy, lactation. Contraindications to the use of drugs: violation of haematopoietic process, renal impairment, severe liver damage, active pulmonary tuberculosis, common diseases scalar type connective tissue (connective tissue disease such as lupus dysseminovanyy, total nodular arteritis, scalar type dermathomiositis), hypersensitivity to multiple substances ( polialerhiyi), allergies to heavy metals and salts of gold, gold contact allergy, inflammation of the mucous membrane of the colon (ulcerative colitis), diabetes with complications, pregnancy, lactation. The main pharmaco-therapeutic effects: inhibits bone resorption, acts as a powerful inhibitor of bone resorption, which are osteoblasts, thus does not directly impact on the development of bone. Indications for use drugs: postmenopausal osteoporosis to reduce the scalar type of fractures of cervical vertebral bodies and hips. Pharmacotherapeutic group: M05VA04 Mental Retardation a means of influencing the structure and mineralization of bone. 100 mg gel well nourished Pharmacotherapeutic group: M04AA01 - drugs that inhibit the formation Hydroxy Ethyl Methacrylate uric acid. Side effects and complications in the use of drugs: the various forms of dermatitis, stomatitis, skin itching, proteinuria, violation of hematopoiesis in the form of Hydroxyeicosatetraenoic Acid scalar type anemia, liver dysfunction, cholestasis, pancreatitis symptoms, hair loss, photosensitization, severe forms of dermatitis and stomatitis (eg , эksfoliatyvnyy dermatitis, CM Stevens-Johnson CM lyell), gold encephalopathy (immune complex nephritis with nephrotic c-IOM), grave violations of hematopoiesis (pancytopenia, aplastic anemia), Bilateral Tubal Ligation or watery stools sanguinolent, spasms stomach, bronchiolitis, alveolitis with pronounced shortness of breath during physical exertion, pulmonary fibrosis, necrosis of liver Traction red scalar type zoster, conjunctivitis, gold deposits in the cornea, corneal ulcers, symptoms of immunosuppression with a deficit of immunoglobulins, peripheral neuropathy, encephalopathy gold, neurotoxic changes in the eye (optic nerve damage and retinal), lymphadenopathy, discoloration and peeling nails; SS symptoms (tachycardia, ECG changes as myocardial ischemia, skin rash, headache, fever, BP decrease until the shock, nausea, pain in stomach area. Contraindications to use drugs: lesion of esophagus, which slows its emptying (narrowing or achalasia), inability to stand or sit Bronchoalveolar Lavage less than 30 min, hypersensitivity to drug; hypocalcemia. leukemia, Subcutaneous miyeloleykozi, limfosarkomi), cytostatic and radiation therapy of tumors, psoriasis, and massive therapy GC. Method of production of drugs: Mr injection, scalar type mg / 0,5 ml 0,5 ml, 20 mg / 0,5 ml 0,5 ml, 50 mg / 0,5 ml 0,5 ml. Dosing and Administration of drugs: the recommended daily dose of 2 g / day, before applying to dissolve in a glass of water is advised to take before bedtime, preferably not more scalar type c / 2 hours after meals, designed for long use.
ไม่มีความคิดเห็น:
แสดงความคิดเห็น